Brandon Wahl scored a game-high 32 points and Derek Zeller scored 15 to lead the Leopards to a 73-53 road victory against the Quakers. Cameron King also scored 9 and Spencer Hall added 8 for LHS.
Erin Hahn scored 16 points but Louisville fell to Marlington 49-46. Ellie Jackson also scored 8 points, Hanna Lautzenheiser had 7, and Rachel Israel grabbed 9 rebounds.
Louisville avenged an earlier season loss with a 42-24 victory over the Beaver Local Beavers in the Regional Semifinals. The Leopards built a 25-6 lead in the Regional Final before the host Canfield Cardinals stormed back to win 33-31.
Spencer Hall scored a team-high 13 points and Colton Jones hit 4 three-pointers, but the Leopards were edged by the visiting Bulldogs 58-56. Davis Burick also scored 10 and Brandon Wahl added 9 for 10-5 Louisville.
Ellie Jackson scored 6 points and recorded 4 steals, but the Leopards fell on the road to the Quakers 52-35. Sydney Bast and Hanna Lautzenheiser also scored 5 points each for Louisville.