Louisville Leopards Football 1985
- Head Coach: Doug Schwall (1st Year)
- Overall Record: 4-6
- Federal League: 1-5
- Home 2-3, Away 2-3
- GlenOak Golden Eagles and Perry Panthers Co-Federal League Champions (5-1)
1985 Louisville Leopards Football Schedule
| Week | Date | Opponent | W-L | Louisville | Opponent | |
| 1 | 8/30 | Kent Roosevelt | L | 6 | 9 | |
| 2 | 9/6 | at Canton South | L | 8 | 9 | |
| 3 | 9/13 | at Alliance | W | 13 | 10 | 3 OT |
| 4 | 9/20 | Lake | W | 23 | 0 | |
| 5 | 9/27 | GlenOak | L | 0 | 24 | |
| 6 | 10/4 | at Jackson | L | 12 | 37 | |
| 7 | 10/11 | Marlington | W | 28 | 22 | OT |
| 8 | 10/18 | at Canton Timken | W | 17 | 13 | |
| 9 | 10/25 | North Canton Hoover | L | 7 | 16 | |
| 10 | 11/1 | at Perry | L | 0 | 34 |
Note: The Week 3 game at Alliance was the first overtime game in Louisville Football history.
