Louisville trailed 16-4 in the second quarter, but two big runs helped them pull ahead for a 43-31 victory. Hollyann Mullett led the Leopards with 12, Rachel Zeller scored 10, and Taylor Noble added 7.
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The Dukes finished the game on a 15-2 run to win their first home game against the Leopards since 1996 by a count of 44-42. Hollyann Mullett scored a game-high 18 points for Louisville.