Louisville Leopards Football Playoff History Log
Overall: 14-17 | Home: 4-7 | Away: 3-0 | Neutral: 7-10
| Date | Division/Game | Opponent | W-L | Louisville | Opponent | Location |
| 11/8/1991 | DII Regional Semifinal | Lake | L | 0 | 13 | Jackson Robert Fife Stadium |
| 11/13/1992 | DII Regional Semifinal | Revere | W | 28 | 14 | Canton Fawcett Stadium |
| 11/20/1992 | DII, Regional Final | Youngstown Chaney | W | 34 | 6 | Boardman Spartan Stadium |
| 11/27/1992 | DII, State Semifinal | Fostoria | L | 7 | 48 | Baldwin-Wallace George Finnie Stadium |
| 11/12/1993 | DII, Regional Semifinal | Lake | L | 33 | 48 | North Canton Memorial Stadium |
| 11/5/1999 | DIII, Regional Quarterfinal | Thornville Sheridan | L | 7 | 14 | Louisville Stadium |
| 11/4/2000 | DIII, Regional Quarterfinal | Canfield | L | 7 | 21 | Louisville Stadium |
| 11/2/2001 | DII, Regional Quarterfinal | Chardon | L | 6 | 21 | Louisville Stadium |
| 11/1/2002 | DII, Regional Quarterfinal | Youngstown Chaney | W | 17 | 7 | Louisville Stadium |
| 11/8/2002 | DII, Regional Semifinal | Olmsted Falls | L | 20 | 21 | Canton Fawcett Stadium |
| 10/31/2003 | DII, Regional Quarterfinal | Pickerington Central | W | 35 | 34 | Pickerington Tiger Stadium |
| 11/7/2003 | DII, Regional Semifinal | Columbus Independence | L | 26 | 49 | Coshocton Stewart Field |
| 11/5/2004 | DII, Regional Quarterfinal | New Philadelphia | W | 18 | 7 | New Philadelphia Woody Hayes Quaker Stadium |
| 11/12/2004 | DII, Regional Semifinal | Lake | L | 0 | 24 | Canton Fawcett Stadium |
| 11/4/2005 | DII, Regional Quarterfinal | Dublin Jerome | W | 48 | 13 | Louisville Stadium |
| 11/11/2005 | DII, Regional Semifinal | Dublin Scioto | W | 28 | 23 | Lexington Minutemen Stadium |
| 11/18/2005 | DII, Regional Final | Canfield | L | 0 | 7 | Warren Mollenkopf Stadium |
| 11/2/2007 | DII, Regional Quarterfinal | Lake | W | 34 | 21 | Louisville Stadium |
| 11/9/2007 | DII, Regional Semifinal | Dresden Tri-Valley | W | 22 | 13 | New Philadelphia Woody Hayes Quaker Stadium |
| 11/16/2007 | DII, Regional Final | Columbus St. Francis DeSales | W | 25 | 20 | Lexington Minutemen Stadium |
| 11/23/2007 | DII, State Semifinal | Mayfield | W | 41 | 13 | Bedford Bearcat Stadium |
| 11/30/2007 | DII, State Championship | Cincinnati Andersen | L | 25 | 31 | Massillon Paul Brown Tiger Stadium |
| 10/31/2008 | DII, Regional Quarterfinal | Columbus Independence | W | 60 | 24 | Louisville Stadium |
| 11/7/2008 | DII, Regional Semifinal | Logan | W | 7 | 0 | Zanesville John D. Sulsberger Stadium |
| 11/14/2008 | DII, Regional Final | Columbus St. Francis DeSales | L | 21 | 38 | Mansfield Arlin Field |
| 11/6/2009 | DII, Regional Quarterfinal | Columbus Marion-Franklin | L | 7 | 14 | Louisville Stadium |
| 11/8/2013 | DIII, Regional Quarterfinal | Aurora | L | 21 | 24 | Louisville Leopards Stadium |
| 11/7/2014 | DIII, Regional Quarterfinal | Poland Seminary | L | 21 | 41 | Louisville Leopards Stadium |
| 11/6/2015 | DIII, Regional Quarterfinal | Poland Seminary | W | 42 | 7 | Dave Pavlansky Field |
| 11/13/2015 | DIII, Regional Semifinal | Archbishop Hoban | L | 14 | 21 | Green Memorial Stadium |
| 10/9/2020 | DIII, Region 9 Round 1 | Notre Dame-Cathedral Latin | L | 7 | 14 | Louisville Leopards Stadium |
